7qny

X-ray diffraction
2.84Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-225185 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
COVOX-58 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 232 amino acids
Theoretical weight: 24.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
COVOX-58 light chain Chain: B
Molecule details ›
Chain: B
Length: 214 amino acids
Theoretical weight: 22.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chain: E
Molecule details ›
Chain: E
Length: 202 amino acids
Theoretical weight: 22.86 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 333-528; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
COVOX-158 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
COVOX-158 light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3121
Unit cell:
a: 72.762Å b: 72.762Å c: 416.202Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.229 0.226 0.278
Expression system: Homo sapiens