› 7uwp

X-ray diffraction
1.95Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125865 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Obtusifoliol 14alphademethylase, putative Chains: A, B
Molecule details ›
Chains: A, B
Length: 460 amino acids
Theoretical weight: 52.45 KDa
Source organism: Acanthamoeba castellanii
Expression system: Escherichia coli
UniProt:
  • Canonical: L8GJB3 (Residues: 43-486; Coverage: 91%)
Gene name: ACA1_372720
Sequence domains: Cytochrome P450

Ligands and Environments


Cofactor: Ligand HEM 2 x HEM
1 bound ligand:
Ligand LMT 2 x LMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 100.397Å b: 101.561Å c: 122.004Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.225
Expression system: Escherichia coli

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