7ws5

Electron Microscopy
3.7Å resolution

Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-535487 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1205 amino acids
Theoretical weight: 133.94 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-210, 211-211, 215-1208; Coverage: 94%)
Gene names: 2, S
Sequence domains:
510A5 light chain Chains: D, F, H
Molecule details ›
Chains: D, F, H
Length: 108 amino acids
Theoretical weight: 11.68 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
510A5 heavy chain Chains: E, G, I
Molecule details ›
Chains: E, G, I
Length: 123 amino acids
Theoretical weight: 13.59 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-32744
Expression system: Homo sapiens