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Electron Microscopy
3.5Å resolution

SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab in the class 2 conformation

Released:
Entry authors: Guo H, Gao Y, Lu Y, Yang H, Ji X
Related structures: EMD-32867

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-210384 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1205 amino acids
Theoretical weight: 133.94 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-210, 211-211, 215-1208; Coverage: 94%)
Gene names: 2, S
Sequence domains:
55A8 light chain Chains: F, H
Molecule details ›
Chains: F, H
Length: 108 amino acids
Theoretical weight: 11.87 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
55A8 heavy chain Chains: G, I
Molecule details ›
Chains: G, I
Length: 121 amino acids
Theoretical weight: 13.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-32867
Expression system: Homo sapiens