› 7xgd

Electron Microscopy
4Å resolution

Cryo-EM structure of Apo-IGF1R map 1

Released:
DOI: 10.2210/pdb7xgd/pdb
PDB entry 7xgd coloured by chain, front view.
PDB entry 7xgd coloured by chain, side view.
PDB entry 7xgd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhang X, Wu C
Related structures: EMD-33186

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139911 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin-like growth factor 1 receptor alpha chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 897 amino acids
Theoretical weight: 102.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P08069 (Residues: 31-927; Coverage: 67%)
Gene name: IGF1R
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 4 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4Å
Relevant EMDB volumes: EMD-33186
Expression system: Homo sapiens

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