7z8k

Electron Microscopy
4.37Å resolution

Cytoplasmic dynein (A1) bound to BICDR1

Released:
Related structures: EMD-14555

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-106082 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Cytoplasmic dynein 1 light intermediate chain 2 Chain: i
Molecule details ›
Chain: i
Length: 492 amino acids
Theoretical weight: 54.17 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O43237 (Residues: 1-492; Coverage: 100%)
Gene names: DNCLI2, DYNC1LI2, LIC2
Sequence domains: Dynein light intermediate chain (DLIC)
Cytoplasmic dynein 1 intermediate chain 2 Chain: h
Molecule details ›
Chain: h
Length: 567 amino acids
Theoretical weight: 63.12 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q13409 (Residues: 72-638; Coverage: 89%)
Gene names: DNCI2, DNCIC2, DYNC1I2
Sequence domains:
BICD family-like cargo adapter 1 Chains: W, X, w, x
Molecule details ›
Chains: W, X, w, x
Length: 577 amino acids
Theoretical weight: 65.38 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: A0JNT9 (Residues: 1-577; Coverage: 100%)
Gene names: Bicdl1, Bicdr1, Ccdc64
Alpha-centractin Chain: F
Molecule details ›
Chain: F
Length: 376 amino acids
Theoretical weight: 42.67 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: F2Z5G5 (Residues: 1-310; Coverage: 89%)
Gene name: ACTR1A
Sequence domains: Actin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.37Å
Relevant EMDB volumes: EMD-14555
Expression system: Spodoptera frugiperda