7zet

X-ray diffraction
2.8Å resolution

Crystal structure of human Clusterin, crystal form I

Released:
Source organism: Homo sapiens
Entry authors: Yuste-Checa P, Bracher A, Hartl FU

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-231754 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Clusterin Chain: A
Molecule details ›
Chain: A
Length: 402 amino acids
Theoretical weight: 47.04 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P10909 (Residues: 23-449; Coverage: 94%)
Gene names: AAG4, APOJ, CLI, CLU, KUB1
Sequence domains: Clusterin

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 65.742Å b: 43.808Å c: 102.8Å
α: 90° β: 107.29° γ: 90°
R-values:
R R work R free
0.235 0.232 0.274
Expression system: Homo sapiens