7ado

Electron Microscopy
3.39Å resolution

Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-279351 (preferred)
Entry contents:
10 distinct polypeptide molecules
Macromolecules (10 distinct):
ER membrane protein complex subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 993 amino acids
Theoretical weight: 111.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
ER membrane protein complex subunit 2 Chain: B
Molecule details ›
Chain: B
Length: 297 amino acids
Theoretical weight: 34.88 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
ER membrane protein complex subunit 3 Chain: C
ER membrane protein complex subunit 4 Chain: D
ER membrane protein complex subunit 5 Chain: E
ER membrane protein complex subunit 6 Chain: F
Endoplasmic reticulum membrane protein complex subunit 7 Chain: G
ER membrane protein complex subunit 8 Chain: H
ER membrane protein complex subunit 10 Chain: I
Unassigned helix Chain: K

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.39Å
Relevant EMDB volumes: EMD-11732
Expression system: Homo sapiens