EC 3.6.4.12: DNA helicase
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (DNA helix unwinding)
Alternative Name(s):
- 3' to 5' DNA helicase
- 3'-5' DNA helicase
- 3'-5' PfDH
- 5' to 3' DNA helicase
- AvDH1
- BACH1 helicase
- BLM protein
- BRCA1-associated C-terminal helicase
- BcMCM
- CeWRN-1
- DNA helicase 120
- DNA helicase A
- DNA helicase E
- DNA helicase II
- DNA helicase III
- DNA helicase RECQL5'
- DNA helicase VI
- Dbp9p
- DmRECQ5
- DnaB
- DnaB helicase E1
- HHcsA
- HPif1
- Hel E
- Helicase DnaB
- Helicase HDH IV
- Helicase domain of bacteriophage T7 gene 4 protein helicase
- Hmi1p
- MCM helicase
- MCM protein
- MER3 helicase
- MER3 protein
- MPH1
- PDH120
- PIF1
- PcrA
- PcrA helicase
- PfDH A
- Pfh1p
- UvrD
GO terms
Biochemical function:
Biological process:
- regulation of double-strand break repair
- positive regulation of double-strand break repair via homologous recombination
- positive regulation of telomere maintenance in response to DNA damage
- telomerase RNA localization to Cajal body
- regulation of DNA strand elongation
- regulation of cell cycle
- chromosome organization
- protein stabilization
- regulation of embryonic development
- positive regulation of DNA-templated transcription
- positive regulation of DNA repair
- regulation of apoptotic process
- regulation of chromosome organization
- DNA duplex unwinding
- regulation of transcription by RNA polymerase II
- regulation of DNA-templated transcription
- chromatin remodeling
- chromatin organization
- DNA recombination
- regulation of DNA repair
- DNA repair
- regulation of DNA replication
- telomere maintenance
- box C/D snoRNP assembly
Cellular component:
- ribonucleoprotein complex
- RPAP3/R2TP/prefoldin-like complex
- dynein axonemal particle
- protein folding chaperone complex
- R2TP complex
- MLL1 complex
- extracellular exosome
- NuA4 histone acetyltransferase complex
- Ino80 complex
- nuclear matrix
- membrane
- cytosol
- centrosome
- cytoplasm
- nucleoplasm
- nucleus
- Swr1 complex
- nucleosome
Protein families (Pfam)
InterPro annotations