Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Coagulation factor IXa complex and antibody (preferred)
PDBe Complex ID:
PDB-CPX-524054 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Coagulation factor IXa light chain
Molecule details ›
Chain: L
Length: 59 amino acids
Theoretical weight: 6.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Coagulation Factor Xa inhibitory site
Length: 59 amino acids
Theoretical weight: 6.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P00740 (Residues: 130-188; Coverage: 14%)
Sequence domains: Coagulation Factor Xa inhibitory site
Coagulation factor IXa heavy chain
Molecule details ›
Chain: H
Length: 235 amino acids
Theoretical weight: 26.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Trypsin
Length: 235 amino acids
Theoretical weight: 26.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P00740 (Residues: 227-461; Coverage: 54%)
Sequence domains: Trypsin
