7akd

Electron Microscopy
4Å resolution

Structure of the SARS-CoV-2 spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-210135 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (9 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1286 amino acids
Theoretical weight: 141.68 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:
47D11 neutralizing antibody heavy chain Chains: D, H
Molecule details ›
Chains: D, H
Length: 121 amino acids
Theoretical weight: 13.21 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
47D11 neutralizing antibody light chain Chains: E, L
Molecule details ›
Chains: E, L
Length: 106 amino acids
Theoretical weight: 11.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, MAN, BMA
Carbohydrate polymer : NEW Components: NAG, FUC, BMA
Carbohydrate polymer : NEW Components: NAG, FUC, MAN, BMA
Carbohydrate polymer : NEW Components: MAN
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-11812
Expression system: Homo sapiens