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Electron Microscopy
3.8Å resolution

Structure of the SARS-CoV spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-548086 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1193 amino acids
Theoretical weight: 132.3 KDa
Source organism: SARS coronavirus WH20
Expression system: Homo sapiens
47D11 neutralizing antibody heavy chain Chains: E, G, H
Molecule details ›
Chains: E, G, H
Length: 121 amino acids
Theoretical weight: 13.21 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
47D11 neutralizing antibody light chain Chains: D, F, L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer : NEW Components: NAG, FUC, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-11813
Expression system: Homo sapiens