› 7amn

X-ray diffraction
2.3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-502926 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 221 amino acids
Theoretical weight: 25.3 KDa
Source organism: Vibrio alginolyticus
Expression system: Escherichia coli
UniProt:
  • Canonical: B4X9Q4 (Residues: 1-204; Coverage: 100%)
Gene names: F0254_10710, GHY86_04250, HKB35_07570, valR
Sequence domains: Bacterial regulatory proteins, tetR family
DNA (5'-D(P*TP*AP*TP*TP*GP*AP*TP*AP*AP*AP*AP*TP*TP*AP*TP*CP*AP*AP*TP*AP*A)-3') Chain: E
Molecule details ›
Chain: E
Length: 21 nucleotides
Theoretical weight: 6.45 KDa
Source organism: Vibrio alginolyticus
Expression system: Not provided
DNA (5'-D(P*TP*TP*AP*TP*TP*GP*AP*TP*AP*AP*TP*TP*TP*TP*AP*TP*CP*AP*AP*TP*A)-3') Chain: F
Molecule details ›
Chain: F
Length: 21 nucleotides
Theoretical weight: 6.43 KDa
Source organism: Vibrio alginolyticus
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P41
Unit cell:
a: 69.339Å b: 69.339Å c: 123.206Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.21 0.242
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

1 review citation

A domain swapping strategy to create modular transcriptional regulators for novel topology in genetic network.
Chan et al. (2024)
7 other articles

2 mentions without citation

Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression.
Zhang et al. (2021)
1 more