› 7ane

Electron Microscopy
3.9Å resolution

Leishmania Major mitochondrial ribosome

Released:
DOI: 10.2210/pdb7ane/pdb
PDB entry 7ane coloured by chain, front view.
PDB entry 7ane coloured by chain, side view.
PDB entry 7ane coloured by chain, top view.
Source organism: Leishmania major
Primary publication:
Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Soufari H, Waltz F, Parrot C, Durrieu-Gaillard S, Bochler A, Kuhn L, Sissler M, Hashem Y
Proc Natl Acad Sci U S A 117 29851-29861 (2020)
PMID: 33168716
Related structures: EMD-11829

Function and Biology Details

Reactions catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
3-hydroxy-2-methylpropanoyl-CoA + H(2)O = CoA + 3-hydroxy-2-methylpropanoate
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 124-mer (preferred)
PDBe Complex ID:
PDB-CPX-123135 (preferred)
Entry contents:
122 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (123 distinct):
uS14m Chain: h
Molecule details ›
Chain: h
Length: 166 amino acids
Theoretical weight: 19.55 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QIP8 (Residues: 1-166; Coverage: 100%)
Gene name: LMJF_07_0450
mS69 Chain: aw
Molecule details ›
Chain: aw
Length: 139 amino acids
Theoretical weight: 16.3 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QHA2 (Residues: 1-139; Coverage: 100%)
Gene name: LMJF_10_1120
Mitochondrial ribosomal protein S18 Chain: m
Molecule details ›
Chain: m
Length: 325 amino acids
Theoretical weight: 37.79 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q1J0 (Residues: 1-325; Coverage: 100%)
Gene name: LMJF_36_2310
uS11m Chain: f
Molecule details ›
Chain: f
Length: 371 amino acids
Theoretical weight: 40.97 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QJG8 (Residues: 1-371; Coverage: 100%)
Gene name: LMJF_05_0340
mS33 Chain: s
Molecule details ›
Chain: s
Length: 179 amino acids
Theoretical weight: 20.89 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ACZ5 (Residues: 1-179; Coverage: 100%)
Gene name: LMJF_27_0180
Rhodanese domain-containing protein Chain: au
Molecule details ›
Chain: au
Length: 247 amino acids
Theoretical weight: 30.14 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q6T5 (Residues: 1-247; Coverage: 100%)
Gene name: LMJF_30_3530
Sequence domains: Rhodanese-like domain
mS59 Chain: am
Molecule details ›
Chain: am
Length: 313 amino acids
Theoretical weight: 35.76 KDa
Source organism: Leishmania major
uS19m Chain: n
Molecule details ›
Chain: n
Length: 171 amino acids
Theoretical weight: 19.61 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q7N2 (Residues: 1-171; Coverage: 100%)
Gene name: LMJF_30_0740
mS53 Chain: ae
Molecule details ›
Chain: ae
Length: 655 amino acids
Theoretical weight: 72.16 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QFA7 (Residues: 1-655; Coverage: 100%)
Gene name: LMJF_15_0780
mS71 Chain: ay
Molecule details ›
Chain: ay
Length: 169 amino acids
Theoretical weight: 19.87 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q7W4 (Residues: 1-169; Coverage: 100%)
Gene name: LMJF_28_2980
Pentacotripeptide-repeat region of PRORP domain-containing protein Chain: ag
Molecule details ›
Chain: ag
Length: 564 amino acids
Theoretical weight: 65.16 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ADP4 (Residues: 1-564; Coverage: 100%)
Gene name: LMJF_29_0430
mS57 Chain: aj
Molecule details ›
Chain: aj
Length: 397 amino acids
Theoretical weight: 45.73 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q7Q8 (Residues: 1-397; Coverage: 100%)
Gene name: LMJF_30_0650
LysM domain-containing protein Chain: e
Molecule details ›
Chain: e
Length: 822 amino acids
Theoretical weight: 92.51 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q4M2 (Residues: 1-822; Coverage: 100%)
Gene name: LMJF_33_0010
Sequence domains: LysM domain
Ribosomal protein S9 Chain: d
Molecule details ›
Chain: d
Length: 351 amino acids
Theoretical weight: 39.58 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QB37 (Residues: 1-351; Coverage: 100%)
Gene name: LMJF_23_1190
Sequence domains: Ribosomal protein S9/S16
mS72 Chain: az
Molecule details ›
Chain: az
Length: 163 amino acids
Theoretical weight: 19.49 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QBM5 (Residues: 1-163; Coverage: 100%)
Gene name: LMJF_22_1220
mS70 Chain: ax
Molecule details ›
Chain: ax
Length: 184 amino acids
Theoretical weight: 21.52 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q103 (Residues: 1-184; Coverage: 100%)
Gene name: LMJF_36_4120
Small ribosomal subunit protein mS29 Chain: r
Molecule details ›
Chain: r
Length: 467 amino acids
Theoretical weight: 54.25 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QGU0 (Residues: 1-467; Coverage: 100%)
Gene name: LMJF_12_0040
Sequence domains: Mitochondrial ribosomal death-associated protein 3
Excreted/secreted protein 15 Chain: af
Molecule details ›
Chain: af
Length: 835 amino acids
Theoretical weight: 92.4 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q1X7J7 (Residues: 1-835; Coverage: 100%)
Mitochondrial SSU ribosomal protein Chain: u
Molecule details ›
Chain: u
Length: 890 amino acids
Theoretical weight: 99.58 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9AD40 (Residues: 1-890; Coverage: 100%)
Gene name: LMJF_27_0630
mS48 Chain: aa
Molecule details ›
Chain: aa
Length: 1813 amino acids
Theoretical weight: 199.81 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QEP4 (Residues: 1-1813; Coverage: 100%)
Gene name: LMJF_16_1230
mS49 Chain: ab
Molecule details ›
Chain: ab
Length: 1177 amino acids
Theoretical weight: 133.17 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ADG8 (Residues: 1-1177; Coverage: 100%)
Gene name: LMJF_27_1895
mS58 Chain: ak
Molecule details ›
Chain: ak
Length: 325 amino acids
Theoretical weight: 36.07 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ACK8 (Residues: 1-325; Coverage: 100%)
Gene name: LMJF_03_0630
mS50 Chain: ac
Molecule details ›
Chain: ac
Length: 1267 amino acids
Theoretical weight: 139.23 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QBP8 (Residues: 1-1267; Coverage: 100%)
Gene name: LMJF_22_0990
mS51 Chain: ad
Molecule details ›
Chain: ad
Length: 811 amino acids
Theoretical weight: 94.54 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QAQ0 (Residues: 1-811; Coverage: 100%)
Gene name: LMJF_24_0830
mS60 Chain: an
Molecule details ›
Chain: an
Length: 302 amino acids
Theoretical weight: 35.16 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QBR4 (Residues: 1-302; Coverage: 100%)
Gene names: LMJF_22_0710, LMJF_22_0830
mS61 Chain: ao
Molecule details ›
Chain: ao
Length: 291 amino acids
Theoretical weight: 33.4 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9AF47 (Residues: 1-291; Coverage: 100%)
Gene name: LMJF_35_2230
mS62 Chain: ap
Molecule details ›
Chain: ap
Length: 245 amino acids
Theoretical weight: 27.47 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q847 (Residues: 1-245; Coverage: 100%)
Gene name: LMJF_28_2180
mS63 Chain: aq
Molecule details ›
Chain: aq
Length: 295 amino acids
Theoretical weight: 33.83 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QF40 (Residues: 1-295; Coverage: 100%)
Gene name: LMJF_15_1400
mS65 Chain: as
Molecule details ›
Chain: as
Length: 270 amino acids
Theoretical weight: 30.3 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QIF7 (Residues: 1-270; Coverage: 100%)
Gene name: LMJF_08_0120
Probable Zinc-ribbon domain-containing protein Chain: at
Molecule details ›
Chain: at
Length: 397 amino acids
Theoretical weight: 44.35 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QE10 (Residues: 1-397; Coverage: 100%)
Gene name: LMJF_18_0320
Sequence domains: Probable Zinc-ribbon domain
mS43 Chain: y
Molecule details ›
Chain: y
Length: 485 amino acids
Theoretical weight: 51.48 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q3D4 (Residues: 1-485; Coverage: 100%)
Gene name: LMJF_34_0720
Small ribosomal subunit protein mS41 Chain: w
Molecule details ›
Chain: w
Length: 190 amino acids
Theoretical weight: 22.24 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q4E6 (Residues: 1-190; Coverage: 100%)
Gene name: LMJF_33_0600
Sequence domains: IGR protein motif
mS37 Chain: v
Molecule details ›
Chain: v
Length: 214 amino acids
Theoretical weight: 24.32 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QCC8 (Residues: 1-214; Coverage: 100%)
Gene name: LMJF_21_0827
mS34 Chain: t
Molecule details ›
Chain: t
Length: 267 amino acids
Theoretical weight: 29.27 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q8W5 (Residues: 1-267; Coverage: 100%)
Gene name: LMJF_26_2270
mS23 Chain: p
Molecule details ›
Chain: p
Length: 321 amino acids
Theoretical weight: 36.81 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QFH6 (Residues: 1-321; Coverage: 100%)
Gene name: LMJF_15_0080
bS16m Chain: j
Molecule details ›
Chain: j
Length: 189 amino acids
Theoretical weight: 22.47 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q8H5 (Residues: 1-189; Coverage: 100%)
Gene name: LMJF_28_0920
Mitochondrial RNA binding complex 1 subunit Chain: l
Molecule details ›
Chain: l
Length: 677 amino acids
Theoretical weight: 75.47 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q3T6 (Residues: 1-677; Coverage: 100%)
Gene name: LMJF_33_2510
A-kinase anchor protein 7-like phosphoesterase domain-containing protein Chain: ar
Molecule details ›
Chain: ar
Length: 282 amino acids
Theoretical weight: 31.46 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q5L8 (Residues: 1-282; Coverage: 100%)
Gene name: LMJF_32_0650
Sequence domains: AKAP7 2'5' RNA ligase-like domain
Ubiquitin-like domain-containing protein Chain: av
Molecule details ›
Chain: av
Length: 236 amino acids
Theoretical weight: 27.34 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q9M1 (Residues: 1-236; Coverage: 100%)
Gene name: LMJF_25_2160
mS56 Chain: ai
Molecule details ›
Chain: ai
Length: 379 amino acids
Theoretical weight: 43.58 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q6W8 (Residues: 1-379; Coverage: 100%)
Gene name: LMJF_30_3220
Manganese/iron superoxide dismutase C-terminal domain-containing protein Chain: x
Molecule details ›
Chain: x
Length: 268 amino acids
Theoretical weight: 30.37 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q716 (Residues: 1-268; Coverage: 100%)
Gene name: LMJF_30_2770
Sequence domains: Iron/manganese superoxide dismutases, C-terminal domain
uS15m Chain: i
Molecule details ›
Chain: i
Length: 429 amino acids
Theoretical weight: 50.38 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QCY9 (Residues: 1-429; Coverage: 100%)
Gene name: LMJF_20_0510
bS21m Chain: g
Molecule details ›
Chain: g
Length: 192 amino acids
Theoretical weight: 22.84 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9AE13 (Residues: 1-192; Coverage: 100%)
Gene name: LMJF_29_1540
Chromosome passenger complex (CPC) protein INCENP N terminal Chain: o
Molecule details ›
Chain: o
Length: 604 amino acids
Theoretical weight: 73.15 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9AFL9 (Residues: 1-604; Coverage: 100%)
Gene name: LMJF_35_3940
Ribosomal protein S8 Chain: c
Molecule details ›
Chain: c
Length: 311 amino acids
Theoretical weight: 35.1 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QDW2 (Residues: 1-311; Coverage: 100%)
Gene name: LMJF_18_0800
Sequence domains: Ribosomal protein S8
30S Ribosomal protein S17-like protein Chain: k
Molecule details ›
Chain: k
Length: 312 amino acids
Theoretical weight: 36.02 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9AFK9 (Residues: 1-312; Coverage: 100%)
Gene name: LMJF_35_3850
Sequence domains: Ribosomal protein S17
mS26 Chain: q
Molecule details ›
Chain: q
Length: 425 amino acids
Theoretical weight: 49.49 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9AFH3 (Residues: 2-426; Coverage: 100%)
Gene name: LMJF_35_3490
Ribosomal protein S6 Chain: b
Molecule details ›
Chain: b
Length: 159 amino acids
Theoretical weight: 18.82 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q3G8 (Residues: 1-159; Coverage: 100%)
Gene name: LMJF_34_0400
Ribosomal_S5_C domain-containing protein Chain: a
Molecule details ›
Chain: a
Length: 431 amino acids
Theoretical weight: 49.35 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q1N8 (Residues: 1-431; Coverage: 100%)
Gene name: LMJF_36_1860
Sequence domains:
mS73 Chain: ba
Molecule details ›
Chain: ba
Length: 94 amino acids
Theoretical weight: 11.38 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q6W6 (Residues: 2-95; Coverage: 99%)
Gene name: LMJF_30_3235
3-hydroxyisobutyryl-CoA hydrolase Chain: z
Molecule details ›
Chain: z
Length: 1169 amino acids
Theoretical weight: 131.57 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q190 (Residues: 2-1170; Coverage: 100%)
Gene name: LMJF_36_3280
Sequence domains: Enoyl-CoA hydratase/isomerase
uS3m Chain: bd
Molecule details ›
Chain: bd
Length: 89 amino acids
Theoretical weight: 10.68 KDa
Source organism: Leishmania major
Ribosomal protein L3-like protein Chain: A
Molecule details ›
Chain: A
Length: 466 amino acids
Theoretical weight: 53.89 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ADK5 (Residues: 2-467; Coverage: 100%)
Gene name: LMJF_29_0030
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4m Chain: B
Molecule details ›
Chain: B
Length: 435 amino acids
Theoretical weight: 49.87 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QGU6 (Residues: 2-436; Coverage: 100%)
Gene name: LMJF_11_1360
Sequence domains: Ribosomal protein L4/L1 family
Ribosomal protein L9 domain-containing protein Chain: C
Molecule details ›
Chain: C
Length: 261 amino acids
Theoretical weight: 30.38 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QIE5 (Residues: 2-262; Coverage: 100%)
Gene name: LMJF_08_0240
Sequence domains: Ribosomal protein L9, N-terminal domain
uL10m Chain: D
Molecule details ›
Chain: D
Length: 204 amino acids
Theoretical weight: 22.17 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QI77 (Residues: 1-204; Coverage: 100%)
Gene name: LMJF_08_0920
Large ribosomal subunit protein uL11m Chain: E
Molecule details ›
Chain: E
Length: 345 amino acids
Theoretical weight: 40.14 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ACT9 (Residues: 2-346; Coverage: 100%)
Gene name: LMJF_27_2220
Sequence domains:
50S ribosomal protein L13-like protein Chain: F
Molecule details ›
Chain: F
Length: 171 amino acids
Theoretical weight: 20.5 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q2H6 (Residues: 1-171; Coverage: 100%)
Gene name: LMJF_34_3680
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL15/eL18 domain-containing protein Chain: G
Molecule details ›
Chain: G
Length: 373 amino acids
Theoretical weight: 43.44 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QF19 (Residues: 2-374; Coverage: 100%)
Gene name: LMJF_16_0010
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Ribosomal_L16 domain-containing protein Chain: H
Molecule details ›
Chain: H
Length: 167 amino acids
Theoretical weight: 19 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QFP0 (Residues: 2-168; Coverage: 99%)
Gene name: LMJF_14_0950
Sequence domains: Ribosomal protein L16p/L10e
Putative 50S ribosomal protein L17 Chain: I
Molecule details ›
Chain: I
Length: 304 amino acids
Theoretical weight: 35.7 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QF04 (Residues: 2-305; Coverage: 100%)
Gene name: LMJF_16_0160
Sequence domains: Ribosomal protein L17
bL19m Chain: J
Molecule details ›
Chain: J
Length: 143 amino acids
Theoretical weight: 16.56 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QCY7 (Residues: 2-144; Coverage: 99%)
Gene name: LMJF_20_0530
Large ribosomal subunit protein bL20c Chain: K
Molecule details ›
Chain: K
Length: 193 amino acids
Theoretical weight: 22.31 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q192 (Residues: 2-194; Coverage: 100%)
Gene name: LMJF_36_3260
Large ribosomal subunit protein bL21m Chain: L
Molecule details ›
Chain: L
Length: 185 amino acids
Theoretical weight: 20.91 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QFQ5 (Residues: 2-186; Coverage: 100%)
Gene name: LMJF_14_0780
Sequence domains: Ribosomal prokaryotic L21 protein
Large ribosomal subunit protein uL22c Chain: M
Molecule details ›
Chain: M
Length: 278 amino acids
Theoretical weight: 32.15 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QBR0 (Residues: 2-279; Coverage: 100%)
Gene name: LMJF_22_0870
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein uL23m Chain: N
Molecule details ›
Chain: N
Length: 251 amino acids
Theoretical weight: 28.71 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QA05 (Residues: 2-252; Coverage: 100%)
Gene name: LMJF_25_0890
KOW domain-containing protein Chain: O
Molecule details ›
Chain: O
Length: 475 amino acids
Theoretical weight: 53.49 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q9S7 (Residues: 2-476; Coverage: 100%)
Gene name: LMJF_25_1640
bL27m Chain: P
Molecule details ›
Chain: P
Length: 184 amino acids
Theoretical weight: 21.48 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QG34 (Residues: 2-185; Coverage: 100%)
Gene name: LMJF_13_1200
39S ribosomal protein L28, mitochondrial Chain: Q
Molecule details ›
Chain: Q
Length: 233 amino acids
Theoretical weight: 27.09 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q719 (Residues: 2-234; Coverage: 100%)
Gene name: LMJF_30_2750
Large ribosomal subunit protein uL29m Chain: R
Molecule details ›
Chain: R
Length: 479 amino acids
Theoretical weight: 54.1 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q9XZY7 (Residues: 2-480; Coverage: 100%)
Gene name: LMJF_04_0270
Sequence domains: Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
Ribosomal protein L30 ferredoxin-like fold domain-containing protein Chain: S
Molecule details ›
Chain: S
Length: 408 amino acids
Theoretical weight: 45.43 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q9U0Z7 (Residues: 2-409; Coverage: 100%)
Gene name: LMJF_04_0860
bL32m Chain: T
Molecule details ›
Chain: T
Length: 82 amino acids
Theoretical weight: 9.73 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q2W9 (Residues: 2-83; Coverage: 99%)
Gene name: LMJF_34_2310
bL33m Chain: U
Molecule details ›
Chain: U
Length: 117 amino acids
Theoretical weight: 13.34 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q2Q8 (Residues: 2-118; Coverage: 99%)
Gene name: LMJF_34_2860
bL35m Chain: V
Molecule details ›
Chain: V
Length: 150 amino acids
Theoretical weight: 18.26 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QCK6 (Residues: 2-151; Coverage: 99%)
Gene name: LMJF_21_0100
39S ribosomal protein L36, mitochondrial Chain: W
Molecule details ›
Chain: W
Length: 185 amino acids
Theoretical weight: 21.72 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q6A3 (Residues: 2-186; Coverage: 100%)
Gene name: LMJF_31_1590
Phosphatidylethanolamine-binding protein Chain: X
Molecule details ›
Chain: X
Length: 512 amino acids
Theoretical weight: 57.99 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q5A3 (Residues: 2-513; Coverage: 100%)
Gene name: LMJF_32_1770
mL40 Chain: Y
Molecule details ›
Chain: Y
Length: 292 amino acids
Theoretical weight: 33.21 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q448 (Residues: 1-292; Coverage: 100%)
Gene name: LMJF_33_1390
mL41 Chain: Z
Molecule details ›
Chain: Z
Length: 197 amino acids
Theoretical weight: 22.67 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q152 (Residues: 1-197; Coverage: 100%)
Gene name: LMJF_36_3653
Rhodanese domain-containing protein Chain: BA
Molecule details ›
Chain: BA
Length: 167 amino acids
Theoretical weight: 17.89 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ACP5 (Residues: 1-167; Coverage: 100%)
Gene name: LMJF_04_0045
UA Chain: UA
Molecule details ›
Chain: UA
Length: 203 amino acids
Theoretical weight: 17.29 KDa
Source organism: Leishmania major
mL95 Chain: BB
Molecule details ›
Chain: BB
Length: 156 amino acids
Theoretical weight: 18.69 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q4D6 (Residues: 1-156; Coverage: 100%)
Gene name: LMJF_33_0690
mL89 Chain: Aw
Molecule details ›
Chain: Aw
Length: 187 amino acids
Theoretical weight: 21.56 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9AD00 (Residues: 1-187; Coverage: 100%)
Gene name: LMJF_27_0230
bL31m Chain: Bj
Molecule details ›
Chain: Bj
Length: 185 amino acids
Theoretical weight: 21.26 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q0E1 (Residues: 1-185; Coverage: 100%)
Gene name: LMJF_36_6190
mL76 Chain: An
Molecule details ›
Chain: An
Length: 331 amino acids
Theoretical weight: 38.66 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q0F5 (Residues: 1-331; Coverage: 100%)
Gene name: LMJF_36_6050
mL74 Chain: Al
Molecule details ›
Chain: Al
Length: 346 amino acids
Theoretical weight: 39.39 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q1C8 (Residues: 1-346; Coverage: 100%)
Gene name: LMJF_36_2910
Peptidyl-prolyl cis-trans isomerase Chain: BI
Molecule details ›
Chain: BI
Length: 266 amino acids
Theoretical weight: 28.92 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q1A6 (Residues: 1-266; Coverage: 100%)
Gene names: CYP10, LMJF_36_3130
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
mL93 Chain: Az
Molecule details ›
Chain: Az
Length: 152 amino acids
Theoretical weight: 18.86 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q4D9 (Residues: 1-152; Coverage: 100%)
Gene name: LMJF_33_0660
mL86 Chain: At
Molecule details ›
Chain: At
Length: 183 amino acids
Theoretical weight: 21.07 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q4L5 (Residues: 1-183; Coverage: 100%)
Gene name: LMJF_33_0080
mL96 Chain: BC
Molecule details ›
Chain: BC
Length: 147 amino acids
Theoretical weight: 16.71 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q5D8 (Residues: 1-147; Coverage: 100%)
Gene name: LMJF_32_1440
Large ribosomal subunit protein mL43 Chain: Ab
Molecule details ›
Chain: Ab
Length: 262 amino acids
Theoretical weight: 31.23 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q6A7 (Residues: 1-262; Coverage: 100%)
Gene name: LMJF_31_1550
Sequence domains: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
AMP-dependent synthetase/ligase domain-containing protein Chain: Ai
Molecule details ›
Chain: Ai
Length: 479 amino acids
Theoretical weight: 54.18 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q7P8 (Residues: 1-479; Coverage: 100%)
Gene name: LMJF_30_0580
Sequence domains: AMP-binding enzyme
mL80 Chain: Ap
Molecule details ›
Chain: Ap
Length: 240 amino acids
Theoretical weight: 27.95 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q7V3 (Residues: 1-240; Coverage: 100%)
Gene name: LMJF_30_0060
mL87 Chain: Au
Molecule details ›
Chain: Au
Length: 186 amino acids
Theoretical weight: 22.27 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q8J6 (Residues: 1-186; Coverage: 100%)
Gene name: LMJF_28_0730
mL42 Chain: Aa
Molecule details ›
Chain: Aa
Length: 195 amino acids
Theoretical weight: 22.17 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q183 (Residues: 1-195; Coverage: 100%)
Gene name: LMJF_36_3350
mL79 Chain: Ao
Molecule details ›
Chain: Ao
Length: 284 amino acids
Theoretical weight: 33.39 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q547 (Residues: 1-284; Coverage: 100%)
Gene name: LMJF_32_2280
mL70 Chain: BM
Molecule details ›
Chain: BM
Length: 457 amino acids
Theoretical weight: 50.75 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q703 (Residues: 1-457; Coverage: 100%)
Gene name: LMJF_30_2890
mL84 Chain: Ar
Molecule details ›
Chain: Ar
Length: 205 amino acids
Theoretical weight: 24.62 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q712 (Residues: 1-205; Coverage: 100%)
Gene name: LMJF_30_2810
mL72 Chain: Aj
Molecule details ›
Chain: Aj
Length: 503 amino acids
Theoretical weight: 56.55 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q728 (Residues: 1-503; Coverage: 100%)
Gene name: LMJF_30_2660
Peptidyl-prolyl cis-trans isomerase Chain: BH
Molecule details ›
Chain: BH
Length: 229 amino acids
Theoretical weight: 25.31 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QBK2 (Residues: 1-229; Coverage: 100%)
Gene names: CYP6, LMJF_22_1450
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Mitochondrial RNA binding complex 1 subunit Chain: Am
Molecule details ›
Chain: Am
Length: 340 amino acids
Theoretical weight: 39.65 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QC22 (Residues: 1-340; Coverage: 100%)
Gene name: LMJF_21_1620
Sequence domains: PPR repeat family
mL82 Chain: Aq
Molecule details ›
Chain: Aq
Length: 341 amino acids
Theoretical weight: 37.91 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QD92 (Residues: 1-341; Coverage: 100%)
Gene name: LMJF_19_1230
mL98 Chain: BE
Molecule details ›
Chain: BE
Length: 118 amino acids
Theoretical weight: 13.26 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QE16 (Residues: 1-118; Coverage: 100%)
Gene name: LMJF_18_0260
AB hydrolase-1 domain-containing protein Chain: Ak
Molecule details ›
Chain: Ak
Length: 323 amino acids
Theoretical weight: 36.08 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QEC8 (Residues: 1-323; Coverage: 100%)
Gene name: LMJF_17_0760
mL52 Chain: BP
Molecule details ›
Chain: BP
Length: 254 amino acids
Theoretical weight: 29.2 KDa
Source organism: Leishmania major
mL49 Chain: Ad
Molecule details ›
Chain: Ad
Length: 237 amino acids
Theoretical weight: 26.21 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QIB3 (Residues: 1-237; Coverage: 100%)
Gene name: LMJF_08_0560
mL99 Chain: BF
Molecule details ›
Chain: BF
Length: 109 amino acids
Theoretical weight: 13.05 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QIQ1 (Residues: 1-109; Coverage: 100%)
Gene name: LMJF_07_0420
mL88 Chain: Av
Molecule details ›
Chain: Av
Length: 192 amino acids
Theoretical weight: 22.34 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QIT7 (Residues: 1-192; Coverage: 100%)
Gene name: LMJF_07_0070
mL63 Chain: Af
Molecule details ›
Chain: Af
Length: 155 amino acids
Theoretical weight: 18.1 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QJB6 (Residues: 1-155; Coverage: 100%)
Gene name: LMJF_05_0860
mL85 Chain: As
Molecule details ›
Chain: As
Length: 249 amino acids
Theoretical weight: 27.53 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ABZ5 (Residues: 1-249; Coverage: 100%)
Gene name: LMJF_01_0060
Ribosomal protein L9 domain-containing protein Chain: Ae
Molecule details ›
Chain: Ae
Length: 311 amino acids
Theoretical weight: 35.48 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ACG2 (Residues: 1-311; Coverage: 100%)
Gene name: LMJF_03_0150
Large ribosomal subunit protein mL46 Chain: Ac
Molecule details ›
Chain: Ac
Length: 291 amino acids
Theoretical weight: 33.35 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QJ75 (Residues: 1-291; Coverage: 100%)
Gene name: LMJF_06_0040
Sequence domains: 39S mitochondrial ribosomal protein L46
mL68 Chain: Ah
Molecule details ›
Chain: Ah
Length: 570 amino acids
Theoretical weight: 65.79 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QC45 (Residues: 1-570; Coverage: 100%)
Gene name: LMJF_21_1500
mL97 Chain: BD
Molecule details ›
Chain: BD
Length: 102 amino acids
Theoretical weight: 12.08 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QE11 (Residues: 1-102; Coverage: 100%)
Gene name: LMJF_18_0310
C2H2-type domain-containing protein Chain: Ay
Molecule details ›
Chain: Ay
Length: 174 amino acids
Theoretical weight: 20.93 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: E9ADN7 (Residues: 1-174; Coverage: 100%)
Gene name: LMJF_29_0360
mL59/64 Chain: Ag
Molecule details ›
Chain: Ag
Length: 244 amino acids
Theoretical weight: 28.6 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q829 (Residues: 1-244; Coverage: 100%)
Gene name: LMJF_28_2360
LIM zinc-binding domain-containing protein Chain: Ax
Molecule details ›
Chain: Ax
Length: 216 amino acids
Theoretical weight: 25.17 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q7T1 (Residues: 1-216; Coverage: 100%)
Gene name: LMJF_30_0280
Sequence domains: LIM domain
Large ribosomal subunit protein uL2 C-terminal domain-containing protein Chain: BL
Molecule details ›
Chain: BL
Length: 380 amino acids
Theoretical weight: 43.38 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4QIE1 (Residues: 1-380; Coverage: 100%)
Gene name: LMJF_08_0280
Sequence domains: Ribosomal Proteins L2, C-terminal domain
Putative ribosomal protein L14 Chain: BO
Molecule details ›
Chain: BO
Length: 190 amino acids
Theoretical weight: 21.63 KDa
Source organism: Leishmania major
UniProt:
  • Canonical: Q4Q2G1 (Residues: 1-190; Coverage: 100%)
Gene name: LMJF_34_3815
Sequence domains: Ribosomal protein L14p/L23e
mL100 Chain: BG
Molecule details ›
Chain: BG
Length: 1347 amino acids
Theoretical weight: 146.81 KDa
Source organism: Leishmania major
UB Chain: UB
Molecule details ›
Chain: UB
Length: 67 amino acids
Theoretical weight: 5.72 KDa
Source organism: Leishmania major
UC Chain: UC
Molecule details ›
Chain: UC
Length: 144 amino acids
Theoretical weight: 12.27 KDa
Source organism: Leishmania major
UD Chain: UD
Molecule details ›
Chain: UD
Length: 95 amino acids
Theoretical weight: 8.1 KDa
Source organism: Leishmania major
Large ribosomal RNA Chains: 1, 2
Molecule details ›
Chains: 1, 2
Length: 18998 nucleotides
Theoretical weight: 6061.25 KDa
Sequence domains:
  • Trypanosomatid mitochondrial large subunit ribosomal RNA
  • Trypanosomatid mitochondrial small subunit ribosomal RNA

    • Ligands and Environments

    3 bound ligands:
    Ligand ZN 6 x ZN
    Ligand NAD 1 x NAD
    Ligand MG 2 x MG
    No modified residues

    Experiments and Validation Details

    Entry percentile scores
    Resolution: 3.9Å
    Relevant EMDB volumes: EMD-11829

    Quick links

    Citations

    5 review citations

    A Comparative Perspective on Ribosome Biogenesis: Unity and Diversity Across the Tree of Life.
    Jüttner et al. (2022)
    4 more

    1 mention without citation

    Detection of αB-Conotoxin VxXXIVA (αB-CTX) by ic-ELISA Based on an Epitope-Specific Monoclonal Antibody.
    Tang et al. (2022)