› 7aty

Solution NMR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186772 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Caskin-1 Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WXD9 (Residues: 284-346; Coverage: 4%)
Gene names: CASKIN1, KIAA1306
Sequence domains: Variant SH3 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 65%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

A Systematic Compilation of Human SH3 Domains: A Versatile Superfamily in Cellular Signaling.
Mehrabipour et al. (2023)
1 more

1 mention without citation

Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding.
Tőke et al. (2021)