› 7ax3

Electron Microscopy
3.74Å resolution

CryoEM structure of the super-constricted two-start dynamin 1 filament

Released:
DOI: 10.2210/pdb7ax3/pdb
PDB entry 7ax3 coloured by chain, front view.
PDB entry 7ax3 coloured by chain, side view.
PDB entry 7ax3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
CryoEM structure of the super-constricted two-start dynamin 1 filament.
Liu J, Alvarez FJD, Clare DK, Noel JK, Zhang P
OpenAccess logo Nat Commun 12 5393 (2021)
PMID: 34518553
Related structures: EMD-11932

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 36-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170159 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynamin-1 Chains: A, A2, B, B2, C, C2, D, D2, E, E2, F, F2, G, G2, H, H2, I, I2, J, J2, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Molecule details ›
Chains: A, A2, B, B2, C, C2, D, D2, E, E2, F, F2, G, G2, H, H2, I, I2, J, J2, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Length: 864 amino acids
Theoretical weight: 97.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05193 (Residues: 1-864; Coverage: 100%)
Gene names: DNM, DNM1
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand GCP 36 x GCP
Ligand MG 36 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.74Å
Relevant EMDB volumes: EMD-11932
Expression system: Homo sapiens

Quick links

Citations

2 citation in other articles

Brominated lipid probes expose structural asymmetries in constricted membranes.
Moss et al. (2023)
1 more

4 mentions without citation

CryoEM structure of the super-constricted two-start dynamin 1 filament.
Liu et al. (2021)
3 more