› 7b4l

Electron Microscopy
3.1Å resolution

CryoEM structure of the human sodium proton exchanger NHA2

Released:
DOI: 10.2210/pdb7b4l/pdb
PDB entry 7b4l coloured by chain, front view.
PDB entry 7b4l coloured by chain, side view.
PDB entry 7b4l coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Woehlert D, Kuhlbrandt W, Yildiz O
Related structures: EMD-12002

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183179 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sodium/hydrogen exchanger 9B2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 537 amino acids
Theoretical weight: 57.61 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q86UD5 (Residues: 1-537; Coverage: 100%)
Gene names: NHA2, NHEDC2, SLC9B2
Sequence domains: Sodium/hydrogen exchanger family

Ligands and Environments

4 bound ligands:
Ligand NA 2 x NA
Ligand POV 4 x POV
Ligand C14 6 x C14
Ligand UND 10 x UND
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.1Å
Relevant EMDB volumes: EMD-12002
Expression system: Saccharomyces cerevisiae

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