› 7b6u

X-ray diffraction
1.9Å resolution

Sheep Polyomavirus VP1 in complex with 5 mM Forssman antigen pentaose and 20 mM 6'-sialyllactosamine

Released:
DOI: 10.2210/pdb7b6u/pdb
PDB entry 7b6u coloured by chain, front view.
PDB entry 7b6u coloured by chain, side view.
PDB entry 7b6u coloured by chain, top view.
Source organism: Sheep polyomavirus 1
Primary publication:
A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus
Rustmeier NH, Silva LM, Di Maio A, Mueller JC, Herrmann A, Feizi T, Liu Y, Stehle T
Biorxiv (2023)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101220 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Capsid protein VP1 Chains: AAA, BBB, CCC, DDD, EEE, FFF, GGG, HHH, III, JJJ
Molecule details ›
Chains: AAA, BBB, CCC, DDD, EEE, FFF, GGG, HHH, III, JJJ
Length: 276 amino acids
Theoretical weight: 30.58 KDa
Source organism: Sheep polyomavirus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0E3ZCF3 (Residues: 21-292; Coverage: 76%)
Sequence domains: Polyomavirus coat protein

Ligands and Environments

Carbohydrate polymer : NEW Components: SIA, NAG, GAL
Carbohydrate polymer
Carbohydrate polymer : NEW Components: GAL, GLA, NGA, A2G
Carbohydrate polymer
4 bound ligands:
Ligand EDO 7 x EDO
Ligand PEG 12 x PEG
Ligand SIA 1 x SIA
Ligand PGE 2 x PGE
No modified residues

Experiments and Validation Details

Entry percentile scores
R-values:
R R work R free
0.146 0.146 0.173
Expression system: Escherichia coli BL21(DE3)

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