Function and Biology

Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound

Source organism: Saccharomyces cerevisiae
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 3.6.4.13: RNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
  • CSFV NS3 helicase
  • DBP2
  • DDX17
  • DDX25
  • DDX3
  • DDX3X
  • DDX3Y
  • DDX4
  • DDX5
  • DEAD-box RNA helicase
  • DEAD-box protein DED1
  • DEAH-box RNA helicase
  • DEAH-box protein 2
  • DED1
  • DbpA
  • Dex(H/D) RNA helicase
  • EIF4A helicase
  • EhDEAD1
  • EhDEAD1 RNA helicase
  • GRTH/DDX25
  • KOKV helicase
  • Mtr4p
  • NPH-II
  • Nonstructural protein 3 helicase
  • RHA
  • RNA helicase A
  • RNA helicase DDX3
  • RNA helicase Hera
  • RNA-dependent ATPase
  • TGBp1 NTPase/helicase domain
  • VRH1

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Rfam RNA families (Rfam)
RF00004
Domain description: U2 spliceosomal RNA
Occurring in:
  1. U2 snRNA
The deposited structure of PDB entry 7b9v contains 1 copy of Rfam domain RF00004 (U2 spliceosomal RNA) in U2 snRNA. Showing 1 copy in chain A [auth 2].

RF00020
Domain description: U5 spliceosomal RNA
Occurring in:
  1. U5 snRNA
The deposited structure of PDB entry 7b9v contains 1 copy of Rfam domain RF00020 (U5 spliceosomal RNA) in U5 snRNA. Showing 1 copy in chain B [auth 5].

RF00026
Domain description: U6 spliceosomal RNA
Occurring in:
  1. U6 snRNA
The deposited structure of PDB entry 7b9v contains 1 copy of Rfam domain RF00026 (U6 spliceosomal RNA) in U6 snRNA. Showing 1 copy in chain C [auth 6].