Function and Biology

Cys-42-tethered stabilizer 7 of 14-3-3(sigma)/ERa PPI

Source organism: Homo sapiens
Biochemical function: protein sequestering activity
Biological process: negative regulation of stem cell proliferation
Cellular component: extracellular exosome

Sequence family

Pfam Protein family (Pfam)
PF00244
Domain description: 14-3-3 protein
Occurring in:
  1. 14-3-3 protein sigma
The deposited structure of PDB entry 7ba5 contains 1 copy of Pfam domain PF00244 (14-3-3 protein) in 14-3-3 protein sigma. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000308
Domain description: 14-3-3 protein
Occurring in:
  1. 14-3-3 protein sigma
IPR023410
Domain description: 14-3-3 domain
Occurring in:
  1. 14-3-3 protein sigma
IPR036815
Domain description: 14-3-3 domain superfamily
Occurring in:
  1. 14-3-3 protein sigma