Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero 21-mer (preferred)
PDBe Complex ID:
PDB-CPX-136638 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Capsid vertex component 2
Molecule details ›
Chains: G, K
Length: 570 amino acids
Theoretical weight: 62.53 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
Sequence domains: Herpesvirus UL25 family
Length: 570 amino acids
Theoretical weight: 62.53 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
- Canonical:
P03233 (Residues: 1-570; Coverage: 100%)
Sequence domains: Herpesvirus UL25 family
Capsid vertex component 1
Molecule details ›
Chain: C
Length: 507 amino acids
Theoretical weight: 54.53 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
Sequence domains: Herpesvirus UL17 protein
Length: 507 amino acids
Theoretical weight: 54.53 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
- Canonical: P03222 (Residues: 1-507; Coverage: 100%)
Sequence domains: Herpesvirus UL17 protein
Large tegument protein deneddylase
Molecule details ›
Chains: B, O
Length: 3149 amino acids
Theoretical weight: 338.31 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
Sequence domains: Herpesvirus tegument protein, N-terminal conserved region
Length: 3149 amino acids
Theoretical weight: 338.31 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
- Canonical: P03186 (Residues: 1-3149; Coverage: 100%)
Sequence domains: Herpesvirus tegument protein, N-terminal conserved region
Small capsomere-interacting protein
Molecule details ›
Chains: 2, Y, Z, m, y
Length: 176 amino acids
Theoretical weight: 18.17 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
Sequence domains: Gammaherpesvirus capsid protein
Length: 176 amino acids
Theoretical weight: 18.17 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
- Canonical: P14348 (Residues: 1-176; Coverage: 100%)
Sequence domains: Gammaherpesvirus capsid protein
Major capsid protein
Molecule details ›
Chains: S, T, W, l, x
Length: 1381 amino acids
Theoretical weight: 154.09 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
Sequence domains: Herpes virus major capsid protein
Length: 1381 amino acids
Theoretical weight: 154.09 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
- Canonical: P03226 (Residues: 1-1381; Coverage: 100%)
Sequence domains: Herpes virus major capsid protein
Triplex capsid protein 1
Molecule details ›
Chains: 5, e
Length: 364 amino acids
Theoretical weight: 39.23 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
Sequence domains: Herpesvirus capsid shell protein VP19C
Length: 364 amino acids
Theoretical weight: 39.23 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
- Canonical: P03187 (Residues: 1-364; Coverage: 100%)
Sequence domains: Herpesvirus capsid shell protein VP19C
Triplex capsid protein 2
Molecule details ›
Chains: 6, 7, f, g
Length: 301 amino acids
Theoretical weight: 33.65 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
Sequence domains: Herpesvirus VP23 like capsid protein
Length: 301 amino acids
Theoretical weight: 33.65 KDa
Source organism: Human herpesvirus 4 strain B95-8
UniProt:
- Canonical: P25214 (Residues: 1-301; Coverage: 100%)
Sequence domains: Herpesvirus VP23 like capsid protein
