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Atrial Natriuretic Peptide Receptor complexed with deletion mutant of human Atrial Natriuretic Peptide[7-28]

Source organisms:
Biochemical function: hormone activity
Biological process: not assigned
Cellular component: membrane

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EC 4.6.1.2: Guanylate cyclase

Reaction catalysed:
GTP = 3',5'-cyclic GMP + diphosphate
Systematic name:
GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)
Alternative Name(s):
  • GTP diphosphate-lyase (cyclizing)
  • Guanyl cyclase
  • Guanylyl cyclase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF01094
Domain description: Receptor family ligand binding region
Occurring in:
  1. Atrial natriuretic peptide receptor 1
The deposited structure of PDB entry 7brj contains 2 copies of Pfam domain PF01094 (Receptor family ligand binding region) in Atrial natriuretic peptide receptor 1. Showing 1 copy in chain A.

PF00212
Domain description: Atrial natriuretic peptide
Occurring in:
  1. Atriopeptin-2
The deposited structure of PDB entry 7brj contains 1 copy of Pfam domain PF00212 (Atrial natriuretic peptide) in Atriopeptin-2. Showing 1 copy in chain C [auth L].

InterPro InterPro annotations
IPR001170
Domain description: Adenylyl cyclase class-4/guanylyl cyclase
Occurring in:
  1. Atrial natriuretic peptide receptor 1
IPR001828
Domain description: Receptor, ligand binding region
Occurring in:
  1. Atrial natriuretic peptide receptor 1
IPR028082
Domain description: Periplasmic binding protein-like I
Occurring in:
  1. Atrial natriuretic peptide receptor 1
IPR030480
Domain description: Natriuretic peptide, conserved site
Occurring in:
  1. Atriopeptin-2
IPR000663
Domain description: Natriuretic peptide
Occurring in:
  1. Atriopeptin-2

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