› 7brl

X-ray diffraction
3.2Å resolution

Atrial Natriuretic Peptide Receptor complexed with Deletion mutant of rat Atrial Natriuretic Peptide[4-17,23]

Released:
DOI: 10.2210/pdb7brl/pdb
PDB entry 7brl coloured by chain, front view.
PDB entry 7brl coloured by chain, side view.
PDB entry 7brl coloured by chain, top view.
Source organism: Rattus norvegicus
Entry author: Ogawa H

Function and Biology Details

Reaction catalysed: 
GTP = 3',5'-cyclic GMP + diphosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134083 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Atrial natriuretic peptide receptor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 435 amino acids
Theoretical weight: 48.43 KDa
Source organism: Rattus norvegicus
Expression system: Rattus norvegicus
UniProt:
  • Canonical: P18910 (Residues: 29-463; Coverage: 42%)
Gene name: Npr1
Sequence domains: Receptor family ligand binding region
Atriopeptin-1 Chain: L
Molecule details ›
Chain: L
Length: 15 amino acids
Theoretical weight: 1.6 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P01161 (Residues: 126-139; Coverage: 11%)
Gene name: Nppa
Sequence domains: Atrial natriuretic peptide

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P61
Unit cell:
a: 100.273Å b: 100.273Å c: 270.415Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.237
Expression systems:
  • Rattus norvegicus
  • Not provided

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