› 7c36

Solution NMR

c-Myc DNA binding protein structure

Released:
DOI: 10.2210/pdb7c36/pdb
PDB entry 7c36 coloured by chain, ensemble of 20 models, front view.
PDB entry 7c36 coloured by chain, ensemble of 20 models, side view.
PDB entry 7c36 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter.
Aggarwal P, Bhavesh NS
OpenAccess logo Nucleic Acids Res 49 5943-5955 (2021)
PMID: 33999211

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151537 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding motif, single-stranded-interacting protein 1 Chain: A
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 18.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29558 (Residues: 62-223; Coverage: 40%)
Gene names: C2orf12, MSSP, MSSP1, RBMS1, SCR2
Sequence domains: RNA recognition motif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 78%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Interdomain dynamics in human Replication Protein A regulates kinetics and thermodynamics of its binding to ssDNA.
Sangeeta et al. (2023)
2 more

2 mentions without citation

Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter.
Aggarwal et al. (2021)
1 more