Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 180-mer (preferred)
Assembly name:
VP3 and Capsid protein VP2 (preferred)
PDBe Complex ID:
PDB-CPX-101073 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Capsid protein VP1
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 33.2 KDa
Source organism: Coxsackievirus A10
UniProt:
Length: 298 amino acids
Theoretical weight: 33.2 KDa
Source organism: Coxsackievirus A10
UniProt:
- Canonical:
A0A0C5AWF6 (Residues: 565-862; Coverage: 14%)
Capsid protein VP2
Molecule details ›
Chain: B
Length: 255 amino acids
Theoretical weight: 27.78 KDa
Source organism: Coxsackievirus A10
UniProt:
Length: 255 amino acids
Theoretical weight: 27.78 KDa
Source organism: Coxsackievirus A10
UniProt:
- Canonical: G0YPI2 (Residues: 70-324; Coverage: 12%)
Capsid protein VP3
Molecule details ›
Chain: C
Length: 240 amino acids
Theoretical weight: 26.19 KDa
Source organism: Coxsackievirus A10
UniProt:
Length: 240 amino acids
Theoretical weight: 26.19 KDa
Source organism: Coxsackievirus A10
UniProt:
- Canonical: G0YPI2 (Residues: 325-564; Coverage: 11%)
