7c80

Electron Microscopy
3.7Å resolution

E30 F-particle in complex with 4B10

Released:

Function and Biology Details

Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 360-mer (preferred)
PDBe Complex ID:
PDB-CPX-207269 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Light chain Chain: L
Molecule details ›
Chain: L
Length: 221 amino acids
Theoretical weight: 24.33 KDa
Source organism: Mus musculus
Heavy chain Chain: H
Molecule details ›
Chain: H
Length: 206 amino acids
Theoretical weight: 21.73 KDa
Source organism: Mus musculus
VP1 Chain: A
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 33.09 KDa
Source organism: Echovirus E30
VP2 Chain: B
Molecule details ›
Chain: B
Length: 261 amino acids
Theoretical weight: 28.88 KDa
Source organism: Echovirus E30
VP3 Chain: C
Molecule details ›
Chain: C
Length: 238 amino acids
Theoretical weight: 26.16 KDa
Source organism: Echovirus E30
VP4 Chain: D
Molecule details ›
Chain: D
Length: 69 amino acids
Theoretical weight: 7.65 KDa
Source organism: Echovirus E30

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-30303