› 7ch1

Electron Microscopy
2.6Å resolution

The overall structure of SLC26A9

Released:
DOI: 10.2210/pdb7ch1/pdb
PDB entry 7ch1 coloured by chain, front view.
PDB entry 7ch1 coloured by chain, side view.
PDB entry 7ch1 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence.
Chi X, Jin X, Chen Y, Lu X, Tu X, Li X, Zhang Y, Lei J, Huang J, Huang Z, Zhou Q, Pan X
Cell Discov 6 55 (2020)
PMID: 32818062
Related structures: EMD-30368

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute carrier family 26 member 9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 791 amino acids
Theoretical weight: 87.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q7LBE3 (Residues: 1-791; Coverage: 100%)
Gene name: SLC26A9
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand CL 4 x CL
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-30368
Expression system: Homo sapiens

Quick links

Citations

3 review citations

SLC26A9 in airways and intestine: secretion or absorption?
Kunzelmann et al. (2023)
2 more

11 mentions without citation

The progress in C9orf72 research: ALS/FTD pathogenesis, functions and structure.
Jiang et al. (2022)
10 more