› 7civ

X-ray diffraction
1.85Å resolution

Crystal Structure of Agmatine N-Acetyltransferase mutant S171A in complex with Ac-CoA

Released:
DOI: 10.2210/pdb7civ/pdb
PDB entry 7civ coloured by chain, front view.
PDB entry 7civ coloured by chain, side view.
PDB entry 7civ coloured by chain, top view.
Source organism: Drosophila melanogaster
Entry authors: Chen JJ, Hu IC, Lai CH, Lyu PC

Function and Biology Details

Reaction catalysed: 
Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194339 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-acetyltransferase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 216 amino acids
Theoretical weight: 23.78 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9W469 (Residues: 1-216; Coverage: 100%)
Gene names: AANATL8, AgmNAT, CG15766, DmAgmNAT, Dmel\CG15766, Dmel_CG15766
Sequence domains: Acetyltransferase (GNAT) family

Ligands and Environments


Cofactor: Ligand ACO 1 x ACO
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE TPS 05A
Spacegroup: P212121
Unit cell:
a: 44.202Å b: 51.676Å c: 81.928Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.191 0.241
Expression system: Escherichia coli

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