› 7cq7

Electron Microscopy
3.55Å resolution

Structure of the human CLCN7-OSTM1 complex with ADP

Released:
DOI: 10.2210/pdb7cq7/pdb
PDB entry 7cq7 coloured by chain, front view.
PDB entry 7cq7 coloured by chain, side view.
PDB entry 7cq7 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yang GH, Lu YM, Zhang YM, Jia YT, Li XM, Lei JL
Related structures: EMD-30438

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156418 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Osteopetrosis-associated transmembrane protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 344 amino acids
Theoretical weight: 38.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q86WC4 (Residues: 1-334; Coverage: 100%)
Gene names: GL, HSPC019, OSTM1, UNQ6098/PRO21201
Sequence domains: Osteopetrosis-associated transmembrane protein 1 precursor
H(+)/Cl(-) exchange transporter 7 Chains: C, D
Molecule details ›
Chains: C, D
Length: 825 amino acids
Theoretical weight: 90.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P51798 (Residues: 1-805; Coverage: 100%)
Gene name: CLCN7
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand ADP 2 x ADP
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.55Å
Relevant EMDB volumes: EMD-30438
Expression system: Homo sapiens

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