› 7cxg

X-ray diffraction
1.88Å resolution

The ligand-free structure of human PPARgamma LBD Q286E mutant

Released:
DOI: 10.2210/pdb7cxg/pdb
Model geometry
Fit model/data
PDB entry 7cxg coloured by chain, front view.
PDB entry 7cxg coloured by chain, side view.
PDB entry 7cxg coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Jang DM, Han BW

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome proliferator-activated receptor gamma Chains: A, B
Molecule details ›
Chains: A, B
Length: 283 amino acids
Theoretical weight: 32.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P37231 (Residues: 223-505; Coverage: 56%)
Gene names: NR1C3, PPARG
Sequence domains: Ligand-binding domain of nuclear hormone receptor

Ligands and Environments

1 bound ligand:
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: C2
Unit cell:
a: 91.986Å b: 59.886Å c: 117.761Å
α: 90° β: 103.399° γ: 90°
R-values:
R R work R free
0.189 0.187 0.231
Expression system: Escherichia coli

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