› 7cya

X-ray diffraction
1.71Å resolution

Saimiri boliviensis boliviensis galectin-13 with lactose

Released:
DOI: 10.2210/pdb7cya/pdb
PDB entry 7cya coloured by chain, front view.
PDB entry 7cya coloured by chain, side view.
PDB entry 7cya coloured by chain, top view.
Source organism: Saimiri boliviensis boliviensis
Primary publication:
Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site.
Li X, Yao Y, Liu T, Gu K, Han Q, Zhang W, Ayala GJ, Liu Y, Na H, Yu J, Zhang F, Mayo KH, Su J
Glycobiology 31 1219-1229 (2021)
PMID: 34080003

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104312 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 16.49 KDa
Source organism: Saimiri boliviensis boliviensis
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A2K6TQH4 (Residues: 1-139; Coverage: 98%)
Sequence domains: Galactoside-binding lectin

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P21
Unit cell:
a: 33.529Å b: 58.789Å c: 40.833Å
α: 90° β: 113.63° γ: 90°
R-values:
R R work R free
0.177 0.174 0.21
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Heterologous Interactions with Galectins and Chemokines and Their Functional Consequences.
Mayo KH. (2023)
2 other articles