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S protein of SARS-CoV-2 in complex bound with P5A-1B6_3B

Electron Microscopy
3.3Å resolution
PDB entry 7czv coloured by chain, front view.
PDB entry 7czv coloured by chain, side view.
PDB entry 7czv coloured by chain, top view.
Source organisms:
Assembly composition:
hetero nonamer (preferred)
Entry contents: 3 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: SARS-CoV-2 cleaved Spike protein complex
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Multimeric state: hetero nonamer
Accessible surface area: 203355.53 Å2
Buried surface area: 54060.67 Å2
Dissociation area: 2,784.9 Å2
Dissociation energy (ΔGdiss): -20.05 kcal/mol
Dissociation entropy (TΔSdiss): 46.24 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-134441

Macromolecules

Spike glycoprotein
Chains: A, B, C
Length: 1283 amino acids
Theoretical weight: 142.5 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1273; Coverage: 100%)
Gene names: 2, S
Pfam:
InterPro:
Spike glycoprotein in PDB entry 7czv, assembly 1, front view.
Spike glycoprotein in PDB entry 7czv, assembly 1, side view.
Spike glycoprotein in PDB entry 7czv, assembly 1, top view.
Molecule details ›

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Immunoglobulin gamma-1 heavy chain; Immunoglobulin heavy variable 3-30-3
Chains: H, I, J
Length: 457 amino acids
Theoretical weight: 49.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DP02 (Residues: 20-117; Coverage: 100%)
  • Canonical: P0DOX5 (Residues: 99-105, 106-449; Coverage: 78%)
    • nullnull
Gene name: IGHV3-30-3
Pfam:
InterPro:
Immunoglobulin gamma-1 heavy chain in PDB entry 7czv, assembly 1, front view.
Immunoglobulin gamma-1 heavy chain in PDB entry 7czv, assembly 1, side view.
Immunoglobulin gamma-1 heavy chain in PDB entry 7czv, assembly 1, top view.
Molecule details ›

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Ig-like domain-containing protein; Immunoglobulin kappa variable 1-33
Chains: K, M, N
Length: 214 amino acids
Theoretical weight: 23.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8TCD0 (Residues: 21-21, 122-239; Coverage: 54%)
  • Canonical: P01594 (Residues: 24-117; Coverage: 99%)
    • nullnull
Gene name: IGKV1-33
Pfam:
InterPro:
Ig-like domain-containing protein in PDB entry 7czv, assembly 1, front view.
Ig-like domain-containing protein in PDB entry 7czv, assembly 1, side view.
Ig-like domain-containing protein in PDB entry 7czv, assembly 1, top view.
Molecule details ›

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