EC 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1
Reaction catalysed:
S-adenosyl-L-methionine + pseudouridine(1191) in yeast 18S rRNA = S-adenosyl-L-homocysteine + N(1)-methylpseudouridine(1191) in yeast 18S rRNA
Systematic name:
S-adenosyl-L-methionine:18S rRNA (pseudouridine(1191)-N(1))-methyltransferase
Alternative Name(s):
- Nep1
- Nucleolar essential protein 1
EC 3.6.4.13: RNA helicase
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
- CSFV NS3 helicase
- DBP2
- DDX17
- DDX25
- DDX3
- DDX3X
- DDX3Y
- DDX4
- DDX5
- DEAD-box RNA helicase
- DEAD-box protein DED1
- DEAH-box RNA helicase
- DEAH-box protein 2
- DED1
- DbpA
- Dex(H/D) RNA helicase
- EIF4A helicase
- EhDEAD1
- EhDEAD1 RNA helicase
- GRTH/DDX25
- KOKV helicase
- Mtr4p
- NPH-II
- Nonstructural protein 3 helicase
- RHA
- RNA helicase A
- RNA helicase DDX3
- RNA helicase Hera
- RNA-dependent ATPase
- TGBp1 NTPase/helicase domain
- VRH1
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
PF00400
Domain description:
WD domain, G-beta repeat
Occurring in:
Occurring in:
- Ribosomal RNA-processing protein 9
- U3 small nucleolar RNA-associated protein 7
- Protein SOF1
- U3 small nucleolar RNA-associated protein 4
- U3 small nucleolar RNA-associated protein 15
- NET1-associated nuclear protein 1
- Periodic tryptophan protein 2
- U3 small nucleolar RNA-associated protein 12
- U3 small nucleolar RNA-associated protein 13
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 21
PF00004
Domain description:
ATPase family associated with various cellular activities (AAA)
Occurring in:
Occurring in:
PF12923
Domain description:
Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain
Occurring in:
Occurring in:
RNA families (Rfam)
InterPro annotations
IPR001680
Domain description:
WD40 repeat
Occurring in:
Occurring in:
- Ribosomal RNA-processing protein 9
- U3 small nucleolar RNA-associated protein 7
- Protein SOF1
- U3 small nucleolar RNA-associated protein 4
- U3 small nucleolar RNA-associated protein 15
- NET1-associated nuclear protein 1
- Periodic tryptophan protein 2
- U3 small nucleolar RNA-associated protein 12
- U3 small nucleolar RNA-associated protein 13
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 21
IPR015943
Domain description:
WD40/YVTN repeat-like-containing domain superfamily
Occurring in:
Occurring in:
- Ribosomal RNA-processing protein 9
- U3 small nucleolar RNA-associated protein 7
- Protein SOF1
- U3 small nucleolar RNA-associated protein 4
- U3 small nucleolar RNA-associated protein 5
- U3 small nucleolar RNA-associated protein 9
- U3 small nucleolar RNA-associated protein 15
- NET1-associated nuclear protein 1
- Periodic tryptophan protein 2
- U3 small nucleolar RNA-associated protein 12
- U3 small nucleolar RNA-associated protein 13
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 21
IPR036322
Domain description:
WD40-repeat-containing domain superfamily
Occurring in:
Occurring in:
- Ribosomal RNA-processing protein 9
- U3 small nucleolar RNA-associated protein 7
- Protein SOF1
- U3 small nucleolar RNA-associated protein 4
- U3 small nucleolar RNA-associated protein 5
- U3 small nucleolar RNA-associated protein 15
- NET1-associated nuclear protein 1
- Periodic tryptophan protein 2
- U3 small nucleolar RNA-associated protein 12
- U3 small nucleolar RNA-associated protein 13
- U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 21
IPR029063
Domain description:
S-adenosyl-L-methionine-dependent methyltransferase superfamily
Occurring in:
Occurring in:
IPR012173
Domain description:
U3 small nucleolar ribonucleoprotein complex, subunit Mpp10
Occurring in:
Occurring in:
IPR005680
Domain description:
Small ribosomal subunit protein uS12, eukaryotic/archaeal
Occurring in:
Occurring in:
IPR023029
Domain description:
Small ribosomal subunit protein uS15, archaea/eukaryotes
Occurring in:
Occurring in:
IPR004037
Domain description:
Large ribosomal subunit protein eL8-like, conserved site
Occurring in:
Occurring in:
IPR023407
Domain description:
Small ribosomal subunit protein eS27, zinc-binding domain superfamily
Occurring in:
Occurring in:
IPR012678
Domain description:
Ribosomal protein uL23/eL15/eS24 core domain superfamily
Occurring in:
Occurring in:
IPR014721
Domain description:
Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Occurring in:
Occurring in:
IPR028333
Domain description:
Small ribosomal subunit protein uS17, archaeal/eukaryotic
Occurring in:
Occurring in:
IPR005710
Domain description:
Small ribosomal subunit protein uS4, eukaryotic/archaeal
Occurring in:
Occurring in:
IPR042563
Domain description:
Small ribosomal subunit protein eS8 subdomain, eukaryotes
Occurring in:
Occurring in:
IPR038237
Domain description:
Small ribosomal subunit protein eS4, central domain superfamily
Occurring in:
Occurring in:
IPR018199
Domain description:
Small ribosomal subunit protein eS4, N-terminal, conserved site
Occurring in:
Occurring in:
IPR002464
Domain description:
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Occurring in:
Occurring in:
IPR046523
Domain description:
U3 small nucleolar RNA-associated protein 20, C-terminal
Occurring in:
Occurring in:
IPR011430
Domain description:
U3 small nucleolar RNA-associated protein 20, N-terminal
Occurring in:
Occurring in:
IPR036553
Domain description:
RNA 3'-terminal phosphate cyclase, insert domain superfamily
Occurring in:
Occurring in:
IPR013792
Domain description:
RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta
Occurring in:
Occurring in:
IPR048058
Domain description:
rRNA biogenesis protein RRP5, S1 domain, eleventh repeat
Occurring in:
Occurring in:
IPR041054
Domain description:
Exosome complex exonuclease Rrp40, N-terminal domain, eukaryotes
Occurring in:
Occurring in:
IPR013934
Domain description:
U3 small nucleolar RNA-associated protein 13, C-terminal
Occurring in:
Occurring in:
IPR018983
Domain description:
U3 small nucleolar RNA-associated protein 15, C-terminal
Occurring in:
Occurring in:
IPR022125
Domain description:
U3 small nucleolar RNA-associated protein 10, N-terminal
Occurring in:
Occurring in: