› 7dah

X-ray diffraction
2.92Å resolution

Adenosine triphosphate phosphoribosyltransferase from Vibrio cholerae in complex with ATP and PRPP

Released:
DOI: 10.2210/pdb7dah/pdb
PDB entry 7dah coloured by chain, front view.
PDB entry 7dah coloured by chain, side view.
PDB entry 7dah coloured by chain, top view.
Source organism: Vibrio cholerae M66-2
Entry authors: Pal RK, Gourinath S, Biswal BK

Function and Biology Details

Reaction catalysed: 
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192076 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP phosphoribosyltransferase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 310 amino acids
Theoretical weight: 34.58 KDa
Source organism: Vibrio cholerae M66-2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9KSX4 (Residues: 1-298; Coverage: 100%)
Gene names: VC_1132, hisG
Sequence domains:

Ligands and Environments

7 bound ligands:
Ligand PEG 2 x PEG
Ligand EDO 8 x EDO
Ligand PO4 2 x PO4
Ligand GOL 2 x GOL
Ligand MG 2 x MG
Ligand ATP 2 x ATP
Ligand PRP 2 x PRP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P32
Unit cell:
a: 136.603Å b: 136.603Å c: 121.931Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.219 0.216 0.268
Expression system: Escherichia coli BL21(DE3)

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