› 7dej

X-ray diffraction
2.7Å resolution

Structure of human ORP3 ORD in apo-form

Released:
DOI: 10.2210/pdb7dej/pdb
PDB entry 7dej coloured by chain, front view.
PDB entry 7dej coloured by chain, side view.
PDB entry 7dej coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Tong J, Tan L, Im YJ
OpenAccess logo PLoS One 16 e0248781 (2021)
PMID: 33857182

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-574393 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxysterol-binding protein-related protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 388 amino acids
Theoretical weight: 44.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H4L5 (Residues: 504-887; Coverage: 43%)
Gene names: KIAA0704, ORP3, OSBP3, OSBPL3
Sequence domains: Oxysterol-binding protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P3121
Unit cell:
a: 95.912Å b: 95.912Å c: 188.897Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.233 0.285
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Mechanisms of Non-Vesicular Exchange of Lipids at Membrane Contact Sites: Of Shuttles, Tunnels and, Funnels.
Egea PF. (2021)
1 more

1 mention without citation

Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Tong et al. (2021)