7dg5

X-ray diffraction
2Å resolution

Crystal structure of mouse Smc1-Smc3 hinge domain containing a D574Y mutation

Released:
Model geometry
Fit model/data

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-190012 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Structural maintenance of chromosomes protein 1A Chains: A, C
Molecule details ›
Chains: A, C
Length: 215 amino acids
Theoretical weight: 24.63 KDa
Source organism: Mus musculus
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: Q9CU62 (Residues: 471-685; Coverage: 17%)
Gene names: Sb1.8, Smc1, Smc1a, Smc1l1, Smcb
Sequence domains: SMC proteins Flexible Hinge Domain
Structural maintenance of chromosomes protein 3 Chains: B, D
Molecule details ›
Chains: B, D
Length: 213 amino acids
Theoretical weight: 24.34 KDa
Source organism: Mus musculus
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: Q9CW03 (Residues: 484-696; Coverage: 18%)
Gene names: Bam, Bmh, Cspg6, Mmip1, Smc3, Smc3l1, Smcd
Sequence domains: SMC proteins Flexible Hinge Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P1
Unit cell:
a: 50.08Å b: 60.851Å c: 77.757Å
α: 72.66° β: 88.43° γ: 89.99°
R-values:
R R work R free
0.221 0.219 0.269
Expression system: Escherichia coli K-12