› 7dyc

X-ray diffraction
2.3Å resolution

Crystal structure of the chemically synthesized mk2h_deltaMILPYS peptide homodimer in complex with malate

Released:
DOI: 10.2210/pdb7dyc/pdb
PDB entry 7dyc coloured by chain, front view.
PDB entry 7dyc coloured by chain, side view.
PDB entry 7dyc coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
Yagi S, Padhi AK, Vucinic J, Barbe S, Schiex T, Nakagawa R, Simoncini D, Zhang KYJ, Tagami S
J Am Chem Soc 143 15998-16006 (2021)
PMID: 34559526

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
mk2h_deltaMILPYS protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 48 amino acids
Theoretical weight: 5.12 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand MLT 1 x MLT
Ligand LMR 1 x LMR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P3121
Unit cell:
a: 52.278Å b: 52.278Å c: 146.731Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.229 0.226 0.262
Expression system: Not provided

Quick links

Citations

2 review citations

Peptides before and during the nucleotide world: an origins story emphasizing cooperation between proteins and nucleic acids.
Fried et al. (2022)
1 more