› 7dzg

X-ray diffraction
1.6Å resolution

Intermediate of FABP with a delay time of 30 ns

Released:
DOI: 10.2210/pdb7dzg/pdb
Model geometry
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PDB entry 7dzg coloured by chain, front view.
PDB entry 7dzg coloured by chain, side view.
PDB entry 7dzg coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Liu X, Liu P, Li H, Xu Z, Jia L, Xia Y, Yu M, Tang W, Zhu X, Chen C, Zhang Y, Nango E, Tanaka R, Luo F, Kato K, Nakajima Y, Kishi S, Yu H, Matsubara N, Owada S, Tono K, Iwata S, Yu LJ, Shen JR, Wang J
Nat Chem (2022)
PMID: 35851837

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139400 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, liver Chains: A, B
Molecule details ›
Chains: A, B
Length: 137 amino acids
Theoretical weight: 15.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07148 (Residues: 2-127; Coverage: 99%)
Gene names: FABP1, FABPL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

1 bound ligand:
Ligand PLM 2 x PLM
1 modified residue:
Ligand HP9 2 x HP9

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SACLA BEAMLINE BL3
Spacegroup: P212121
Unit cell:
a: 57.67Å b: 66.7Å c: 69.07Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.202
Expression system: Escherichia coli

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Citations

2 citation in other articles

Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity.
Zelencova-Gopejenko et al. (2023)
1 more

1 mention without citation

Binding asymmetry and conformational studies of the AtGSDA dimer.
Jia et al. (2023)

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