7e5o

X-ray diffraction
2.8Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-534768 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
NT-193 Heavy chain Chain: H
Molecule details ›
Chain: H
Length: 244 amino acids
Theoretical weight: 26.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
NT-193 Light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 215 amino acids
Theoretical weight: 24.15 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 322-536; Coverage: 17%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P212121
Unit cell:
a: 84.073Å b: 106.886Å c: 148.074Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.226 0.256
Expression system: Homo sapiens