› 7e66

X-ray diffraction
2.84Å resolution

The crystal structure of peptidoglycan peptidase in complex with inhibitor 3-1

Released:
DOI: 10.2210/pdb7e66/pdb
PDB entry 7e66 coloured by chain, front view.
PDB entry 7e66 coloured by chain, side view.
PDB entry 7e66 coloured by chain, top view.
Source organism: Campylobacter jejuni
Primary publication:
Structure-based inhibitor design for reshaping bacterial morphology
Choi Y, Park JS, Kim J, Min K, Mahasenan K, Kim C, Yoon HJ, Lim S, Cheon DH, Lee Y, Ryu S, Mobashery S, Kim BM, Lee HH
Commun Biol 5 395- (2022)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidase M23 Chain: A
Molecule details ›
Chain: A
Length: 255 amino acids
Theoretical weight: 28.46 KDa
Source organism: Campylobacter jejuni
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand HY6 1 x HY6
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P61
Unit cell:
a: 115.41Å b: 115.41Å c: 56.99Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.215 0.213 0.241
Expression system: Escherichia coli

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