7egf

Electron Microscopy
3.16Å resolution

TFIID lobe A subcomplex

Released:
Source organism: Homo sapiens
Related structures: EMD-31115

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-126216 (preferred)
Entry contents:
10 distinct polypeptide molecules
Macromolecules (10 distinct):
TATA-box-binding protein Chain: P
Molecule details ›
Chain: P
Length: 339 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P20226 (Residues: 1-339; Coverage: 100%)
Gene names: GTF2D1, TBP, TF2D, TFIID
Sequence domains: Transcription factor TFIID (or TATA-binding protein, TBP)
Transcription initiation factor TFIID subunit 3 Chain: c
Molecule details ›
Chain: c
Length: 929 amino acids
Theoretical weight: 103.77 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q5VWG9 (Residues: 1-929; Coverage: 100%)
Gene name: TAF3
Sequence domains:
Transcription initiation factor TFIID subunit 4 Chain: d
Molecule details ›
Chain: d
Length: 1085 amino acids
Theoretical weight: 110.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O00268 (Residues: 1-1085; Coverage: 100%)
Gene names: TAF2C, TAF2C1, TAF4, TAF4A, TAFII130, TAFII135
Sequence domains:
Transcription initiation factor TFIID subunit 5 Chain: e
Molecule details ›
Chain: e
Length: 800 amino acids
Theoretical weight: 86.93 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q15542 (Residues: 1-800; Coverage: 100%)
Gene names: TAF2D, TAF5
Sequence domains:
Transcription initiation factor TFIID subunit 6 Chain: f
Molecule details ›
Chain: f
Length: 677 amino acids
Theoretical weight: 72.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P49848 (Residues: 1-677; Coverage: 100%)
Gene names: TAF2E, TAF6, TAFII70
Sequence domains:
Transcription initiation factor TFIID subunit 9 Chain: i
Molecule details ›
Chain: i
Length: 264 amino acids
Theoretical weight: 29.01 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q16594 (Residues: 1-264; Coverage: 100%)
Gene names: TAF2G, TAF9, TAFII31
Sequence domains: Transcription initiation factor IID, 31kD subunit
Transcription initiation factor TFIID subunit 10 Chain: j
Molecule details ›
Chain: j
Length: 218 amino acids
Theoretical weight: 21.73 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q12962 (Residues: 1-218; Coverage: 100%)
Gene names: TAF10, TAF2A, TAF2H, TAFII30
Sequence domains: Transcription initiation factor TFIID 23-30kDa subunit
Transcription initiation factor TFIID subunit 11 Chain: k
Molecule details ›
Chain: k
Length: 211 amino acids
Theoretical weight: 23.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q15544 (Residues: 1-211; Coverage: 100%)
Gene names: PRO2134, TAF11, TAF2I
Sequence domains: hTAFII28-like protein conserved region
Transcription initiation factor TFIID subunit 12 Chain: l
Molecule details ›
Chain: l
Length: 161 amino acids
Theoretical weight: 17.95 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q16514 (Residues: 1-161; Coverage: 100%)
Gene names: TAF12, TAF15, TAF2J, TAFII20
Sequence domains: Transcription initiation factor TFIID subunit A
Transcription initiation factor TFIID subunit 13 Chain: m
Molecule details ›
Chain: m
Length: 124 amino acids
Theoretical weight: 14.31 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q15543 (Residues: 1-124; Coverage: 100%)
Gene names: TAF13, TAF2K, TAFII18
Sequence domains: Transcription initiation factor IID, 18kD subunit

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.16Å
Relevant EMDB volumes: EMD-31115
Expression system: Homo sapiens