› 7ego

X-ray diffraction
1.21Å resolution

X-ray structure of the human heart fatty acid-binding protein complexed with the fluorescent probe HA527

Released:
DOI: 10.2210/pdb7ego/pdb
PDB entry 7ego coloured by chain, front view.
PDB entry 7ego coloured by chain, side view.
PDB entry 7ego coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Takabayashi M, Yokota J, Matsuoka S, Tsuchikawa H, Sonoyama M, Inoue Y, Hayashi F, Sugiyama S

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138660 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, heart Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05413 (Residues: 1-133; Coverage: 100%)
Gene names: FABP11, FABP3, MDGI
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

2 bound ligands:
Ligand J3R 1 x J3R
Ligand P6G 2 x P6G
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 54.521Å b: 69.657Å c: 33.844Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.13 0.129 0.152
Expression system: Escherichia coli

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