› 7eif

X-ray diffraction
1.58Å resolution

Crystal structure of GAS41 YEATS domain

Released:
DOI: 10.2210/pdb7eif/pdb
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PDB entry 7eif coloured by chain, front view.
PDB entry 7eif coloured by chain, side view.
PDB entry 7eif coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Kikuchi M, Takase S, Konuma T, Noritsugu K, Sekine S, Ikegami T, Ito A, Umehara T
Proc Natl Acad Sci U S A 120 e2304103120 (2023)
PMID: 37844223

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131952 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
YEATS domain-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 17.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95619 (Residues: 19-159; Coverage: 62%)
Gene names: GAS41, YEATS4
Sequence domains: YEATS family

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: C2
Unit cell:
a: 73.595Å b: 52.834Å c: 57.864Å
α: 90° β: 116.47° γ: 90°
R-values:
R R work R free
0.145 0.144 0.158
Expression system: Escherichia coli

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