› 7ej4

Electron Microscopy
3.6Å resolution

Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25

Released:
DOI: 10.2210/pdb7ej4/pdb
PDB entry 7ej4 coloured by chain, front view.
PDB entry 7ej4 coloured by chain, side view.
PDB entry 7ej4 coloured by chain, top view.
Source organisms:
Entry authors: Yang TJ, Yu PY, Wu HC, Hsu STD
Related structures: EMD-30669

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210172 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1283 amino acids
Theoretical weight: 142.24 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:
RBD-chAb-25, Heavy chain Chains: H, I, J
Molecule details ›
Chains: H, I, J
Length: 447 amino acids
Theoretical weight: 48.95 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
RBD-chAb-25, Light chain Chains: L, M, N
Molecule details ›
Chains: L, M, N
Length: 215 amino acids
Theoretical weight: 23.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 21 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-30669
Expression system: Homo sapiens

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