› 7ek4

X-ray diffraction
2.3Å resolution

prawn ferritin to coordinate with heavy metal ions

Released:
DOI: 10.2210/pdb7ek4/pdb
PDB entry 7ek4 coloured by chain, front view.
PDB entry 7ek4 coloured by chain, side view.
PDB entry 7ek4 coloured by chain, top view.
Source organism: Penaeus japonicus
Primary publication:
Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin.
Wang Y, Zang J, Wang C, Zhang X, Zhao G
OpenAccess logo Int J Mol Sci 22 (2021)
PMID: 34360624

Function and Biology Details

Reaction catalysed: 
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197494 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 169 amino acids
Theoretical weight: 19.39 KDa
Source organism: Penaeus japonicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: T2B7E1 (Residues: 2-170; Coverage: 99%)
Sequence domains: Ferritin-like domain

Ligands and Environments

2 bound ligands:
Ligand HG 6 x HG
Ligand FE 6 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NFPSS BEAMLINE BL19U1
Spacegroup: I4
Unit cell:
a: 125.372Å b: 125.372Å c: 176.189Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.237
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 citation in other articles

Structural Insights Into the Effects of Interactions With Iron and Copper Ions on Ferritin From the Blood Clam Tegillarca granosa.
Ming et al. (2022)
2 more

1 mention without citation

Structural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin.
Wang et al. (2021)