Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 27-mer (preferred)
PDBe Complex ID:
PDB-CPX-106078 (preferred)
Entry contents:
27 distinct polypeptide molecules
Macromolecules (27 distinct):
Mediator of RNA polymerase II transcription subunit 1
Chain: A
Molecule details ›
Chain: A
Length: 1581 amino acids
Theoretical weight: 168.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 1581 amino acids
Theoretical weight: 168.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Unknown Chain (poly A)
Chain: B
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 1.44 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 20 amino acids
Theoretical weight: 1.44 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 4
Chain: D
Molecule details ›
Chain: D
Length: 270 amino acids
Theoretical weight: 29.78 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 270 amino acids
Theoretical weight: 29.78 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 6
Chain: F
Molecule details ›
Chain: F
Length: 246 amino acids
Theoretical weight: 28.46 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 246 amino acids
Theoretical weight: 28.46 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 7
Chain: G
Molecule details ›
Chain: G
Length: 233 amino acids
Theoretical weight: 27.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 233 amino acids
Theoretical weight: 27.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 8
Chain: H
Molecule details ›
Chain: H
Length: 268 amino acids
Theoretical weight: 29.11 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 268 amino acids
Theoretical weight: 29.11 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 9
Chain: I
Molecule details ›
Chain: I
Length: 146 amino acids
Theoretical weight: 16.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 146 amino acids
Theoretical weight: 16.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 10
Chain: J
Molecule details ›
Chain: J
Length: 135 amino acids
Theoretical weight: 15.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 135 amino acids
Theoretical weight: 15.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 11
Chain: K
Molecule details ›
Chain: K
Length: 117 amino acids
Theoretical weight: 13.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 117 amino acids
Theoretical weight: 13.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 14
Chain: N
Molecule details ›
Chain: N
Length: 1454 amino acids
Theoretical weight: 160.79 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 1454 amino acids
Theoretical weight: 160.79 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 15
Chain: O
Molecule details ›
Chain: O
Length: 788 amino acids
Theoretical weight: 86.83 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 788 amino acids
Theoretical weight: 86.83 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 16
Chain: P
Molecule details ›
Chain: P
Length: 841 amino acids
Theoretical weight: 93.14 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 841 amino acids
Theoretical weight: 93.14 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 17
Chain: Q
Molecule details ›
Chain: Q
Length: 651 amino acids
Theoretical weight: 72.98 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 651 amino acids
Theoretical weight: 72.98 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 18
Chain: R
Molecule details ›
Chain: R
Length: 208 amino acids
Theoretical weight: 23.69 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 208 amino acids
Theoretical weight: 23.69 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 19
Chain: S
Molecule details ›
Chain: S
Length: 244 amino acids
Theoretical weight: 26.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 244 amino acids
Theoretical weight: 26.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 20
Chain: T
Molecule details ›
Chain: T
Length: 212 amino acids
Theoretical weight: 23.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 212 amino acids
Theoretical weight: 23.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 21
Chain: U
Molecule details ›
Chain: U
Length: 144 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 144 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 22
Chain: V
Molecule details ›
Chain: V
Length: 200 amino acids
Theoretical weight: 22.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 200 amino acids
Theoretical weight: 22.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 23
Chain: W
Molecule details ›
Chain: W
Length: 1368 amino acids
Theoretical weight: 156.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 1368 amino acids
Theoretical weight: 156.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 24
Chain: X
Molecule details ›
Chain: X
Length: 989 amino acids
Theoretical weight: 110.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 989 amino acids
Theoretical weight: 110.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 25
Chain: Y
Molecule details ›
Chain: Y
Length: 747 amino acids
Theoretical weight: 78.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 747 amino acids
Theoretical weight: 78.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 26
Chain: Z
Molecule details ›
Chain: Z
Length: 600 amino acids
Theoretical weight: 65.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 600 amino acids
Theoretical weight: 65.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 27
Chain: 0
Molecule details ›
Chain: 0
Length: 311 amino acids
Theoretical weight: 35.48 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 311 amino acids
Theoretical weight: 35.48 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 28
Chain: 1
Molecule details ›
Chain: 1
Length: 178 amino acids
Theoretical weight: 19.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 178 amino acids
Theoretical weight: 19.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 29
Chain: 2
Molecule details ›
Chain: 2
Length: 200 amino acids
Theoretical weight: 21.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 200 amino acids
Theoretical weight: 21.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 30
Chain: 3
Molecule details ›
Chain: 3
Length: 178 amino acids
Theoretical weight: 20.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 178 amino acids
Theoretical weight: 20.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Mediator of RNA polymerase II transcription subunit 31
Chain: 4
Molecule details ›
Chain: 4
Length: 131 amino acids
Theoretical weight: 15.83 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 131 amino acids
Theoretical weight: 15.83 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens