› › Metabotropic glutamate receptor 2

Metabotropic glutamate receptor 2 in PDB entry 7epa, assembly 1, front view.
Metabotropic glutamate receptor 2 in PDB entry 7epa, assembly 1, side view.
Metabotropic glutamate receptor 2 in PDB entry 7epa, assembly 1, top view.
Chains: A, B
Length: 822 amino acids
Theoretical weight: 91.11 KDa
Source organism: Homo sapiens
Expression system: mammal environmental sample
UniProt:
  • Canonical: Q14416 (Residues: 19-825; Coverage: 95%)
Gene names: GPRC1B, GRM2, MGLUR2
FASTA Sequence
>pdb|7epa|A B
DYKDDDDEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTYRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLYIILFQPQKNVEFLEVLFQ
PDBe-KB: UniProt Coverage View: Q14416  
1822100200300400500600700800
 
200400600800
UniProt
Q14416
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Variants
 
NC
 
  7epa:B 

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1822100200300400500600700800
 
200400600800
Predicted ligand binding sites
P2Rank
Biophysical parameters
EM validation

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