› 7eya

Electron Microscopy
3.77Å resolution

Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-804 Fab

Released:
DOI: 10.2210/pdb7eya/pdb
PDB entry 7eya coloured by chain, front view.
PDB entry 7eya coloured by chain, side view.
PDB entry 7eya coloured by chain, top view.
Source organisms:
Primary publication:
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Du S, Liu P, Zhang Z, Xiao T, Yasimayi A, Huang W, Wang Y, Cao Y, Xie XS, Xiao J
OpenAccess logo Cell Res 31 1130-1133 (2021)
PMID: 34433900
Related structures: EMD-31380

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209653 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (5 distinct):
Spike glycoprotein Chain: R
Molecule details ›
Chain: R
Length: 1285 amino acids
Theoretical weight: 142.07 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
BD-804L Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 23.59 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
BD-804H Chain: H
Spike protein S1 Chain: N

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.77Å
Relevant EMDB volumes: EMD-31380
Expression system: Homo sapiens

Quick links

Citations

8 review citations

Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants.
Sun et al. (2022)
7 more

4 mentions without citation

Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants.
Wang et al. (2023)
3 more