7fj1

Electron Microscopy
4.43Å resolution

Cryo-EM structure of pseudorabies virus C-capsid

Released:
Source organism: Suid alphaherpesvirus 1
Primary publication:
Structures of pseudorabies virus capsids.
OpenAccess logo Nat Commun 13 1533 (2022)
PMID: 35318331
Related structures: EMD-31611

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 3060-mer (preferred)
PDBe Complex ID:
PDB-CPX-124336 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Major capsid protein Chains: 0, A, S, U, a, e, f, g, l, m, n, p, q, u, w, y
Molecule details ›
Chains: 0, A, S, U, a, e, f, g, l, m, n, p, q, u, w, y
Length: 1330 amino acids
Theoretical weight: 146.1 KDa
Source organism: Suid alphaherpesvirus 1
UniProt:
  • Canonical: G3G8T2 (Residues: 1-1330; Coverage: 100%)
Gene name: UL19
Sequence domains: Herpes virus major capsid protein
UL18 Chains: 1, 2, 3, j, k, o, s, v, x, z
Molecule details ›
Chains: 1, 2, 3, j, k, o, s, v, x, z
Length: 296 amino acids
Theoretical weight: 31.76 KDa
Source organism: Suid alphaherpesvirus 1
UniProt:
  • Canonical: G3G8T3 (Residues: 1-296; Coverage: 100%)
Gene name: UL18
Sequence domains: Herpesvirus VP23 like capsid protein
UL17 protein Chain: B
Molecule details ›
Chain: B
Length: 597 amino acids
Theoretical weight: 64.3 KDa
Source organism: Suid alphaherpesvirus 1
UniProt:
  • Canonical: G3G8T5 (Residues: 1-597; Coverage: 100%)
Gene name: UL17
Sequence domains: Herpesvirus UL17 protein
Small capsomere-interacting protein Chains: E, F, G, H, I, J, K, L, M, N, O, P, Q, R, V
Molecule details ›
Chains: E, F, G, H, I, J, K, L, M, N, O, P, Q, R, V
Length: 103 amino acids
Theoretical weight: 11.51 KDa
Source organism: Suid alphaherpesvirus 1
UniProt:
  • Canonical: G3G8R4 (Residues: 1-103; Coverage: 100%)
Gene names: SCP, UL35
Sequence domains: Herpesvirus UL35 family
UL38 protein Chains: T, h, i, r, t
Molecule details ›
Chains: T, h, i, r, t
Length: 368 amino acids
Theoretical weight: 40.01 KDa
Source organism: Suid alphaherpesvirus 1
UniProt:
  • Canonical: Q85211 (Residues: 1-368; Coverage: 100%)
Gene names: CP(UL38), UL38, ul38
Sequence domains: Herpesvirus capsid shell protein VP19C
UL25 Chains: X, c
Molecule details ›
Chains: X, c
Length: 534 amino acids
Theoretical weight: 57.41 KDa
Source organism: Suid alphaherpesvirus 1
UniProt:
  • Canonical: G3G971 (Residues: 1-534; Coverage: 100%)
Gene name: UL25
Sequence domains: Herpesvirus UL25 family
Peptidase C76 domain-containing protein Chains: Y, Z
Molecule details ›
Chains: Y, Z
Length: 62 amino acids
Theoretical weight: 7.07 KDa
Source organism: Suid alphaherpesvirus 1
UniProt:
  • Canonical: G3G8Y0 (Residues: 3011-3072; Coverage: 2%)
Gene name: UL36

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.43Å
Relevant EMDB volumes: EMD-31611