› 7g0e

X-ray diffraction
1.11Å resolution

Crystal Structure of human FABP5 in complex with 2-[(3-ethoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)carbamoyl]cyclopentene-1-carboxylic acid

Released:
DOI: 10.2210/pdb7g0e/pdb
PDB entry 7g0e coloured by chain, front view.
PDB entry 7g0e coloured by chain, side view.
PDB entry 7g0e coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ehler A, Benz J, Obst U, Ceccarelli-Simona M, Rudolph MG

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein 5 Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q01469 (Residues: 1-135; Coverage: 100%)
Gene name: FABP5
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

4 bound ligands:
Ligand DMS 1 x DMS
Ligand L8T 2 x L8T
Ligand SO4 1 x SO4
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P43212
Unit cell:
a: 62.344Å b: 62.344Å c: 75.663Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.162 0.191
Expression system: Escherichia coli BL21(DE3)

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